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ICD-10-CM 2027

ICD-10 code for coma myxedema

E03.5

Myxedema coma

From the official ICD-10-CM alphabetic index entry “Myxedema (adult) (idiocy) (infantile) (juvenile) › coma”. Page updated September 29, 2026.

About coding coma myxedema

The ICD-10-CM code for coma myxedema is E03.5 (Myxedema coma).

Within E03 (other hypothyroidism), E03.5 is specifically for myxedema coma. Related codes cover congenital hypothyroidism with diffuse goiter (E03.0), congenital hypothyroidism without goiter (E03.1), hypothyroidism due to medicaments and other exogenous substances (E03.2), postinfectious hypothyroidism (E03.3), atrophy of thyroid (acquired) (E03.4), other specified hypothyroidism (E03.8) and hypothyroidism, unspecified (E03.9).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 080 (Nontraumatic Stupor and Coma with MCC, relative weight 1.7472), DRG 081 (Nontraumatic Stupor and Coma without MCC, relative weight 0.806), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 01 (Diseases and Disorders of the Nervous System) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about coma myxedema ICD-10 codes

What is the ICD-10 code for coma myxedema?

E03.5 — Myxedema coma.

Is E03.5 billable?

Yes. E03.5 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E03.5 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E03.5 as a principal diagnosis.

Is E03.5 a CC or MCC?

E03.5 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.