ICD-10-CM 2027
ICD-10 code for general fatigue
From the official ICD-10-CM alphabetic index entry “Fatigue › general”. Page updated September 29, 2026.
About coding general fatigue
The ICD-10-CM code for general fatigue is R53.83 (Other fatigue). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on R53.83.
Within R53.8, choose R53.83 (Other fatigue) only when documentation doesn't support a more specific option: other malaise (R53.81) and chronic fatigue, unspecified (R53.82).
The conditions in its Excludes2 note aren't part of R53.83, but may be coded alongside it if the patient has both: exhaustion and fatigue due to depressive episode (F32.-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific general fatigue codes (official index)
- psychogenic F48.8 — Other specified nonpsychotic mental disorders
Common questions about general fatigue ICD-10 codes
What is the ICD-10 code for general fatigue?
- R53.83 — Other fatigue. More specific codes apply when the documentation supports them: F48.8.
What is the ICD-10 code for psychogenic general fatigue?
- F48.8 — Other specified nonpsychotic mental disorders.
Is R53.83 billable?
- Yes. R53.83 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R53.83 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R53.83 as a principal diagnosis.
Is R53.83 a CC or MCC?
- No. R53.83 is neither a CC nor an MCC under MS-DRG v44.0.