ICD-10-CM 2027 diagnosis code
R53.82Chronic fatigue, unspecified
R53.82 is a valid, billable ICD-10-CM code for chronic fatigue, unspecified. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About R53.82
R53.82 is the ICD-10-CM diagnosis code for chronic fatigue, unspecified. It belongs to category R53 (malaise and fatigue), block R50-R69 (general symptoms and signs) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within R53.8, choose R53.82 (Chronic fatigue, unspecified) only when documentation doesn't support a more specific option: other malaise (R53.81) and other fatigue (R53.83).
Don't report R53.82 together with the conditions in its Excludes1 note: chronic fatigue syndrome (G93.32), myalgic encephalomyelitis (G93.32), other post infection and related fatigue syndromes (G93.39) and postviral fatigue syndrome (G93.31).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 780.71 (chronic fatigue syndrome).
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to R53.82.
› From R53.8 Other malaise and fatigue
- combat exhaustion and fatigue (F43.0)
- congenital debility (P96.9)
- exhaustion and fatigue due to excessive exertion (T73.3)
- exhaustion and fatigue due to exposure (T73.2)
- exhaustion and fatigue due to heat (T67.-)
- exhaustion and fatigue due to pregnancy (O26.8-)
- exhaustion and fatigue due to recurrent depressive episode (F33-)
- exhaustion and fatigue due to senile debility (R54)
Broader instructions also apply from Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Alphabetic index entries
1 entriesTerms in the official ICD-10-CM index that lead to R53.82.
Codes whose notes reference R53.82
- G93.3Excludes1
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services
ICD-9-CM equivalent
Converter →- 780.71Chronic fatigue syndromeexact
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about R53.82
Is R53.82 billable?
- Yes. R53.82 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R53.82 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R53.82 as a principal diagnosis.
Is R53.82 a CC or MCC?
- No. R53.82 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does R53.82 group to?
- R53.82 is used in the MS-DRG v44.0 logic for MS-DRG 947 (Signs and Symptoms with MCC) and MS-DRG 948 (Signs and Symptoms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for R53.82?
- The CMS General Equivalence Mappings map R53.82 to ICD-9-CM 780.71.