R53.8Other malaise and fatigue

R53.8 is the ICD-10-CM diagnosis code for other malaise and fatigue. It belongs to category R53 (malaise and fatigue), block R50-R69 (general symptoms and signs) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within R53, choose R53.8 (Other malaise and fatigue) only when documentation doesn't support a more specific option: neoplastic (malignant) related fatigue (R53.0), weakness (R53.1) and functional quadriplegia (R53.2).

To report this condition, pick the subcode that matches the documentation: R53.81 (malaise), R53.82 (unspecified) and R53.83 (fatigue).

Don't report R53.8 together with the conditions in its Excludes1 note: combat exhaustion and fatigue (F43.0), congenital debility (P96.9), exhaustion and fatigue due to excessive exertion (T73.3), exhaustion and fatigue due to exposure (T73.2) and 4 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.