ICD-10-CM 2027
ICD-10 code for gigantism
From the official ICD-10-CM alphabetic index entry “Gigantism (cerebral) (hypophyseal) (pituitary)”. Page updated September 29, 2026.
About coding gigantism
The ICD-10-CM code for gigantism is E22.0 (Acromegaly and pituitary gigantism). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on E22.0.
Within E22 (hyperfunction of pituitary gland), E22.0 is specifically for Acromegaly and pituitary gigantism. Related codes cover Hyperprolactinemia (E22.1), syndrome of inappropriate secretion of antidiuretic hormone (E22.2), other hyperfunction of pituitary gland (E22.8) and unspecified (E22.9).
Don't report E22.0 together with the conditions in its Excludes1 note: constitutional gigantism (E34.4), constitutional tall stature (E34.4) and increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific gigantism codes (official index)
- constitutional E34.4 — Constitutional tall stature
Don't confuse with (Excludes1 for E22.0)
Common questions about gigantism ICD-10 codes
What is the ICD-10 code for gigantism?
- E22.0 — Acromegaly and pituitary gigantism. More specific codes apply when the documentation supports them: E34.4.
What is the ICD-10 code for constitutional gigantism?
- E34.4 — Constitutional tall stature.
Is E22.0 billable?
- Yes. E22.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E22.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E22.0 as a principal diagnosis.
Is E22.0 a CC or MCC?
- No. E22.0 is neither a CC nor an MCC under MS-DRG v44.0.