ICD-10-CM 2027
ICD-10 code for glucagon excess
From the official ICD-10-CM alphabetic index entry “Excess, excessive, excessively › glucagon”. Page updated September 29, 2026.
About coding glucagon excess
The ICD-10-CM code for glucagon excess is E16.3 (Increased secretion of glucagon).
Within E16 (other disorders of pancreatic internal secretion), E16.3 is specifically for increased secretion of glucagon. Related codes cover drug-induced hypoglycemia without coma (E16.0), other hypoglycemia (E16.1), hypoglycemia, unspecified (E16.2), increased secretion of gastrin (E16.4), other specified disorders of pancreatic internal secretion (E16.8), disorder of pancreatic internal secretion, unspecified (E16.9) and hypoglycemia level (E16.A).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about glucagon excess ICD-10 codes
What is the ICD-10 code for glucagon excess?
- E16.3 — Increased secretion of glucagon.
Is E16.3 billable?
- Yes. E16.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E16.3 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E16.3 as a principal diagnosis.
Is E16.3 a CC or MCC?
- No. E16.3 is neither a CC nor an MCC under MS-DRG v44.0.