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ICD-10-CM 2027

ICD-10 code for Gopalan's syndrome

E53.0

Riboflavin deficiency

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Gopalan's syndrome (burning feet)”. Page updated September 29, 2026.

About coding Gopalan's syndrome

The ICD-10-CM code for Gopalan's syndrome is E53.0 (Riboflavin deficiency).

Within E53 (deficiency of other B group vitamins), E53.0 is specifically for Riboflavin deficiency. Related codes cover Pyridoxine deficiency (E53.1), deficiency of other specified B group vitamins (E53.8) and vitamin B deficiency, unspecified (E53.9).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395) and DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about Gopalan's syndrome ICD-10 codes

What is the ICD-10 code for Gopalan's syndrome?

E53.0 — Riboflavin deficiency.

Is E53.0 billable?

Yes. E53.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E53.0 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E53.0 as a principal diagnosis.

Is E53.0 a CC or MCC?

E53.0 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.