ICD-10-CM 2027
ICD-10 code for Hyperestrogenism
From the official ICD-10-CM alphabetic index entry “Hyperestrogenism (drug-induced) (iatrogenic)”. Page updated September 29, 2026.
About coding Hyperestrogenism
The ICD-10-CM code for Hyperestrogenism is E28.0 (Estrogen excess).
Within E28 (ovarian dysfunction), E28.0 is specifically for estrogen excess. Related codes cover androgen excess (E28.1), polycystic ovarian syndrome (E28.2), primary ovarian failure (E28.3), other ovarian dysfunction (E28.8) and unspecified (E28.9).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about Hyperestrogenism ICD-10 codes
What is the ICD-10 code for Hyperestrogenism?
- E28.0 — Estrogen excess.
Is E28.0 billable?
- Yes. E28.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E28.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E28.0 as a principal diagnosis.
Is E28.0 a CC or MCC?
- No. E28.0 is neither a CC nor an MCC under MS-DRG v44.0.