ICD-10-CM 2027 diagnosis code

E28Ovarian dysfunction

Not billable — use a more specific code

E28 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E28

E28 is the ICD-10-CM diagnosis code for ovarian dysfunction. It belongs to block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: E28.0 (excess), E28.1 (excess), E28.2 (syndrome), E28.3 (failure), E28.8 (dysfunction) and E28.9 (unspecified).

Don't report E28 together with the conditions in its Excludes1 note: isolated gonadotropin deficiency (E23.0) and postprocedural ovarian failure (E89.4-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E28

Coding notes

Excludes1Not coded here — never report together with this code

isolated gonadotropin deficiency (E23.0)
postprocedural ovarian failure (E89.4-)

Notes that apply from higher levels

Instructions written at a parent level also apply to E28.

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E28

N91Excludes1

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about E28

Is E28 billable?: No. E28 is a header code. Report one of its more specific subcodes instead.