ICD-10-CM 2027 diagnosis code
E28.3Primary ovarian failure
E28.3 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E28.3
E28.3 is the ICD-10-CM diagnosis code for primary ovarian failure. It belongs to category E28 (ovarian dysfunction), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.
Within E28 (ovarian dysfunction), E28.3 is specifically for primary ovarian failure. Related codes cover estrogen excess (E28.0), androgen excess (E28.1), polycystic ovarian syndrome (E28.2), other ovarian dysfunction (E28.8) and unspecified (E28.9).
To report this condition, pick the subcode that matches the documentation: E28.31 (menopause) and E28.39 (failure).
Don't report E28.3 together with the conditions in its Excludes1 note: pure gonadal dysgenesis (Q99.1) and Turner's syndrome (Q96.-).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E28.3
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to E28.3.
› From E28 Ovarian dysfunction
Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E28.3
Is E28.3 billable?
- No. E28.3 is a header code. Report one of its more specific subcodes instead.