ICD-10-CM 2027
ICD-10 code for Hyperprothrombinemia
From the official ICD-10-CM alphabetic index entry “Hyperprothrombinemia, causing coagulation factor deficiency”. Page updated September 29, 2026.
About coding Hyperprothrombinemia
The ICD-10-CM code for Hyperprothrombinemia is D68.4 (Acquired coagulation factor deficiency).
Within D68 (other coagulation defects), D68.4 is specifically for acquired coagulation factor deficiency. Related codes cover von Willebrand disease (D68.0), hereditary factor XI deficiency (D68.1), hereditary deficiency of other clotting factors (D68.2), hemorrhagic disorder due to circulating anticoagulants (D68.3), primary thrombophilia (D68.5), other thrombophilia (D68.6), other specified coagulation defects (D68.8) and coagulation defect, unspecified (D68.9).
Don't report D68.4 together with the conditions in its Excludes1 note: vitamin K deficiency of newborn (P53).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
Don't confuse with (Excludes1 for D68.4)
- vitamin K deficiency of newborn (P53)
Common questions about Hyperprothrombinemia ICD-10 codes
What is the ICD-10 code for Hyperprothrombinemia?
- D68.4 — Acquired coagulation factor deficiency.
Is D68.4 billable?
- Yes. D68.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D68.4 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D68.4 as a principal diagnosis.
Is D68.4 a CC or MCC?
- D68.4 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.