ICD-10-CM 2027
ICD-10 code for insulin resistance
From the official ICD-10-CM alphabetic index entry “Resistance, resistant (to) › insulin”. Page updated September 29, 2026.
About coding insulin resistance
The ICD-10-CM code for insulin resistance is E88.819 (Insulin resistance, unspecified). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E88.819.
Within E88.81, choose E88.819 (Insulin resistance, unspecified) only when documentation doesn't support a more specific option: metabolic syndrome (E88.810), insulin resistance syndrome, Type A (E88.811) and other insulin resistance (E88.818).
Use an additional code for: codes for associated conditions.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific insulin resistance codes (official index)
Common questions about insulin resistance ICD-10 codes
What is the ICD-10 code for insulin resistance?
- E88.819 — Insulin resistance, unspecified. More specific codes apply when the documentation supports them: O26.89, E88.818.
Is E88.819 billable?
- Yes. E88.819 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E88.819 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E88.819 as a principal diagnosis.
Is E88.819 a CC or MCC?
- No. E88.819 is neither a CC nor an MCC under MS-DRG v44.0.