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ICD-10-CM 2027 diagnosis code

E88.810Metabolic syndrome

✓ Billable / specific

E88.810 is a valid, billable ICD-10-CM code for metabolic syndrome. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Metabolic syndrome, ICD-10 code for Dysmetabolic syndrome X.

Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E88.810

E88.810 is the ICD-10-CM diagnosis code for metabolic syndrome. It belongs to category E88 (other and unspecified metabolic disorders), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E88.81 (metabolic syndrome and other insulin resistance), E88.810 is specifically for metabolic syndrome. Related codes cover insulin resistance syndrome, Type A (E88.811), other insulin resistance (E88.818) and insulin resistance, unspecified (E88.819).

Use an additional code for: codes for associated conditions.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2024, effective October 1, 2023.

Coding notes

Applicable toConditions and synonyms classified to this code
  • Dysmetabolic syndrome

Notes that apply from higher levels

Instructions written at a parent level also apply to E88.810.

› From E88.81 Metabolic syndrome and other insulin resistance
Use additional code
  • codes for associated manifestations, such as:
  • obesity (E66.-)
› From E88 Other and unspecified metabolic disorders
Excludes1
  • histiocytosis X (chronic) (C96.6)
Use additional code
  • codes for associated conditions

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to E88.810.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2024 (effective 10/1/2023): Added
  • No changes since FY2024.

Common questions about E88.810

Is E88.810 billable?

Yes. E88.810 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E88.810 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E88.810 as a principal diagnosis.

Is E88.810 a CC or MCC?

No. E88.810 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E88.810 group to?

E88.810 is used in the MS-DRG v44.0 logic for MS-DRG 642 (Inborn and Other Disorders of Metabolism). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.