ICD-10-CM 2027
ICD-10 code for late syphilis
From the official ICD-10-CM alphabetic index entry “Syphilis, syphilitic (acquired) › late”. Page updated September 29, 2026.
About coding late syphilis
The ICD-10-CM code for late syphilis is A52.9 (Late syphilis, unspecified). The official index lists 10 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on A52.9.
Within A52, choose A52.9 (unspecified) only when documentation doesn't support a more specific option: cardiovascular and cerebrovascular syphilis (A52.0), symptomatic neurosyphilis (A52.1), Asymptomatic neurosyphilis (A52.2), neurosyphilis, unspecified (A52.3), other symptomatic late syphilis (A52.7) and latent (A52.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859), DRG 868 (Other Infectious and Parasitic Diseases Diagnoses with CC, relative weight 1.0235) and DRG 869 (Other Infectious and Parasitic Diseases Diagnoses without CC/MCC, relative weight 0.6787), in MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific late syphilis codes (official index)
- cardiovascular A52.00 — Cardiovascular syphilis, unspecified
- central nervous system A52.3 — Neurosyphilis, unspecified
- kidney A52.75 — Syphilis of kidney and ureter
- latent or 2 years or more after infection (without manifestations) A52.8 — Late syphilis, latent
- negative spinal fluid test A52.8 — Late syphilis, latent
- serology positive A52.8 — Late syphilis, latent
- paresis A52.17 — General paresis
- specified site NEC A52.79 — Other symptomatic late syphilis
- symptomatic or with manifestations A52.79 — Other symptomatic late syphilis
- tabes A52.11 — Tabes dorsalis
Common questions about late syphilis ICD-10 codes
What is the ICD-10 code for late syphilis?
- A52.9 — Late syphilis, unspecified. More specific codes apply when the documentation supports them: A52.00, A52.3, A52.75, A52.8 and others below.
What is the ICD-10 code for cardiovascular late syphilis?
- A52.00 — Cardiovascular syphilis, unspecified.
What is the ICD-10 code for central nervous system late syphilis?
- A52.3 — Neurosyphilis, unspecified.
What is the ICD-10 code for kidney late syphilis?
- A52.75 — Syphilis of kidney and ureter.
What is the ICD-10 code for paresis late syphilis?
- A52.17 — General paresis.
What is the ICD-10 code for symptomatic or with manifestations late syphilis?
- A52.79 — Other symptomatic late syphilis.
What is the ICD-10 code for tabes late syphilis?
- A52.11 — Tabes dorsalis.
Is A52.9 billable?
- Yes. A52.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A52.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A52.9 as a principal diagnosis.
Is A52.9 a CC or MCC?
- No. A52.9 is neither a CC nor an MCC under MS-DRG v44.0.