ICD-10-CM 2027
ICD-10 code for Microdrepanocytosis anemia
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › microdrepanocytosis”. Page updated September 29, 2026.
About coding Microdrepanocytosis anemia
The ICD-10-CM code for Microdrepanocytosis anemia is D57.40 (Sickle-cell thalassemia without crisis).
Within D57.4, choose D57.40 (without crisis) only when documentation doesn't support a more specific option: unspecified, with crisis (D57.41), beta zero without crisis (D57.42), beta zero with crisis (D57.43), beta plus without crisis (D57.44) and beta plus with crisis (D57.45).
Use an additional code for any associated fever (R50.81).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about Microdrepanocytosis anemia ICD-10 codes
What is the ICD-10 code for Microdrepanocytosis anemia?
- D57.40 — Sickle-cell thalassemia without crisis.
Is D57.40 billable?
- Yes. D57.40 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D57.40 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D57.40 as a principal diagnosis.
Is D57.40 a CC or MCC?
- No. D57.40 is neither a CC nor an MCC under MS-DRG v44.0.