ICD-10-CM 2027
ICD-10 code for myelodysplastic disease
Myelodysplastic disease, not elsewhere classified
From the official ICD-10-CM alphabetic index entry “Disease, diseased › myelodysplastic”. Page updated September 29, 2026.
About coding myelodysplastic disease
The ICD-10-CM code for myelodysplastic disease is C94.6 (Myelodysplastic disease, not elsewhere classified).
Within C94 (other leukemias of specified cell type), C94.6 is specifically for myelodysplastic disease, not elsewhere classified. Related codes cover acute erythroid leukemia (C94.0), acute megakaryoblastic leukemia (C94.2), mast cell leukemia (C94.3), acute panmyelosis with myelofibrosis (C94.4) and other specified leukemias (C94.8).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about myelodysplastic disease ICD-10 codes
What is the ICD-10 code for myelodysplastic disease?
- C94.6 — Myelodysplastic disease, not elsewhere classified.
Is C94.6 billable?
- Yes. C94.6 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C94.6 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C94.6 as a principal diagnosis.
Is C94.6 a CC or MCC?
- C94.6 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.