ICD-10-CM 2027
ICD-10 code for ovary hypofunction
From the official ICD-10-CM alphabetic index entry “Hypofunction › ovary”. Page updated September 29, 2026.
About coding ovary hypofunction
The ICD-10-CM code for ovary hypofunction is E28.39 (Other primary ovarian failure).
Within E28.3, choose E28.39 (Other primary ovarian failure) only when documentation doesn't support a more specific option: premature menopause (E28.31).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC, relative weight 1.8456), DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC, relative weight 1.2974), DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC, relative weight 1.0129) and DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC, relative weight 0.7041), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about ovary hypofunction ICD-10 codes
What is the ICD-10 code for ovary hypofunction?
- E28.39 — Other primary ovarian failure.
Is E28.39 billable?
- Yes. E28.39 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E28.39 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E28.39 as a principal diagnosis.
Is E28.39 a CC or MCC?
- No. E28.39 is neither a CC nor an MCC under MS-DRG v44.0.