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ICD-10-CM 2027

ICD-10 code for Pyracin deficiency

E53.1

Pyridoxine deficiency

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Deficiency, deficient › pyracin (alpha) (beta)”. Page updated September 29, 2026.

About coding Pyracin deficiency

The ICD-10-CM code for Pyracin deficiency is E53.1 (Pyridoxine deficiency).

Within E53 (deficiency of other B group vitamins), E53.1 is specifically for Pyridoxine deficiency. Related codes cover Riboflavin deficiency (E53.0), deficiency of other specified B group vitamins (E53.8) and vitamin B deficiency, unspecified (E53.9).

Don't report E53.1 together with the conditions in its Excludes1 note: pyridoxine-responsive sideroblastic anemia (D64.3).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

Don't confuse with (Excludes1 for E53.1)

  • pyridoxine-responsive sideroblastic anemia (D64.3)

Common questions about Pyracin deficiency ICD-10 codes

What is the ICD-10 code for Pyracin deficiency?

E53.1 — Pyridoxine deficiency.

Is E53.1 billable?

Yes. E53.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E53.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E53.1 as a principal diagnosis.

Is E53.1 a CC or MCC?

No. E53.1 is neither a CC nor an MCC under MS-DRG v44.0.