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ICD-10-PCS 2027 procedure code

XW04308Introduction of Spesolimab Monoclonal Antibody into Central Vein, Percutaneous Approach, New Technology Group 8

✓ Valid for 2027

Short description: Introduce Spesolimab in Central Vein, Perc, New Tech 8

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW04308

XW04308 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with spesolimab monoclonal antibody (qualifier: new technology group 8). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW03308 (peripheral vein).

With a different device, use XW04358 (ifezuntirgene inilparvovec), XW04368 (landiolol antiarrhythmic), XW04378 (tabelecleucel immunotherapy), XW04388 (mineral-based topical hemostatic agent) and XW04398 (odronextamab antineoplastic).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2023, effective October 1, 2022.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
0Spesolimab Monoclonal Antibody

Includes: SPEVIGO(R)

7. Qualifier
8New Technology Group 8

Other versions of this procedure

Different body part

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about XW04308

Is XW04308 a valid ICD-10-PCS code for 2027?

Yes. XW04308 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.