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ICD-10-PCS 2027 procedure code

XW04398Introduction of Inebilizumab-cdon into Central Vein, Percutaneous Approach, New Technology Group 8

✓ Valid for 2027

Short description: Introduce Inebilizumab in Central Vein, Perc, New Tech 8

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW04398

XW04398 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with inebilizumab-cdon (qualifier: new technology group 8). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW03398 (peripheral vein).

With a different device, use XW04308 (alpha1-proteinase inhibitor), XW04358 (ifezuntirgene inilparvovec), XW04368 (landiolol antiarrhythmic), XW04378 (tabelecleucel immunotherapy) and XW04388 (mineral-based topical hemostatic agent).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2023, effective October 1, 2022.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
9Inebilizumab-cdon

Includes: UPLIZNA(R)

7. Qualifier
8New Technology Group 8

Other versions of this procedure

Different body part

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about XW04398

Is XW04398 a valid ICD-10-PCS code for 2027?

Yes. XW04398 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.