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ICD-10-CM 2027 diagnosis code

C22Malignant neoplasm of liver and intrahepatic bile ducts

Not billable — use a more specific code

C22 is a header code, so it can't be reported by itself. Choose one of the 8 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C22

C22 is the ICD-10-CM diagnosis code for malignant neoplasm of liver and intrahepatic bile ducts. It belongs to block C15-C26 (malignant neoplasms of digestive organs) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 8 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: C22.0 (carcinoma), C22.1 (carcinoma), C22.2 (Hepatoblastoma), C22.3 (liver), C22.4 (liver), C22.7 (liver), C22.8 (type) and C22.9 (secondary).

Don't report C22 together with the conditions in its Excludes1 note: malignant neoplasm of biliary tract NOS (C24.9) and secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7).

Use an additional code to identify: alcohol abuse and dependence (F10.-), hepatitis B (B16.-, B18.0-B18.1) and hepatitis C (B17.1-, B18.2).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under C22

Coding notes

Excludes1Not coded here — never report together with this code
  • malignant neoplasm of biliary tract NOS (C24.9)
  • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Use additional codeAdd a secondary code to fully describe the condition

Notes that apply from higher levels

Instructions written at a parent level also apply to C22.

Broader instructions also apply from C15-C26 Malignant neoplasms of digestive organs and Chapter 2: Neoplasms.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about C22

Is C22 billable?

No. C22 is a header code. Report one of its more specific subcodes instead.