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Dx

ICD-10-CM 2027 diagnosis code

D46Myelodysplastic syndromes

Not billable — use a more specific code

D46 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D46

D46 is the ICD-10-CM diagnosis code for myelodysplastic syndromes. It belongs to block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D46.0 (stated), D46.1 (sideroblasts), D46.2 ([RAEB]), D46.4 (unspecified), D46.9 (unspecified), D46.A (dysplasia), D46.B (sideroblasts), D46.C (abnormality) and 1 more.

The conditions in its Excludes2 note aren't part of D46, but may be coded alongside it if the patient has both: drug-induced aplastic anemia (D61.1).

Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D46

Coding notes

Excludes2Not included here — may be reported together if both conditions exist
  • drug-induced aplastic anemia (D61.1)
Use additional codeAdd a secondary code to fully describe the condition
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes that apply from higher levels

Instructions written at a parent level also apply to D46.

Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.

Codes whose notes reference D46

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D46

Is D46 billable?

No. D46 is a header code. Report one of its more specific subcodes instead.