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Dx

ICD-10-CM 2027 diagnosis code

D21Other benign neoplasms of connective and other soft tissue

Not billable — use a more specific code

D21 is a header code, so it can't be reported by itself. Choose one of the 8 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D21

D21 is the ICD-10-CM diagnosis code for other benign neoplasms of connective and other soft tissue. It belongs to block D10-D36 (benign neoplasms, except benign neuroendocrine tumors) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 8 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D21.0 (neck), D21.1 (shoulder), D21.2 (hip), D21.3 (thorax), D21.4 (abdomen), D21.5 (pelvis), D21.6 (unspecified) and D21.9 (unspecified).

Don't report D21 together with the conditions in its Excludes1 note: benign neoplasm of articular cartilage (D16.-), benign neoplasm of cartilage of larynx (D14.1), benign neoplasm of cartilage of nose (D14.0), benign neoplasm of connective tissue of breast (D24.-) and 9 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D21

Coding notes

IncludesFurther defines the content of the category
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat
  • benign neoplasm of ligament, except uterine
  • benign neoplasm of lymphatic channel
  • benign neoplasm of muscle
  • benign neoplasm of synovia
  • benign neoplasm of tendon (sheath)
  • benign stromal tumors
Excludes1Not coded here — never report together with this code
  • benign neoplasm of articular cartilage (D16.-)
  • benign neoplasm of cartilage of larynx (D14.1)
  • benign neoplasm of cartilage of nose (D14.0)
  • benign neoplasm of connective tissue of breast (D24.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • benign neoplasm of peritoneum (D20.1)
  • benign neoplasm of retroperitoneum (D20.0)
  • benign neoplasm of uterine ligament, any (D28.2)
  • benign neoplasm of vascular tissue (D18.-)
  • hemangioma (D18.0-)
  • lipomatous neoplasm (D17.-)
  • lymphangioma (D18.1)
  • uterine leiomyoma (D25.-)

Notes that apply from higher levels

Instructions written at a parent level also apply to D21.

Broader instructions also apply from Chapter 2: Neoplasms.

Codes whose notes reference D21

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D21

Is D21 billable?

No. D21 is a header code. Report one of its more specific subcodes instead.