ICD-10-CM 2027 diagnosis code
D38.5Neoplasm of uncertain behavior of other respiratory organs
D38.5 is a valid, billable ICD-10-CM code for neoplasm of uncertain behavior of other respiratory organs. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About D38.5
D38.5 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of other respiratory organs. It belongs to category D38 (neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within D38, choose D38.5 (other respiratory organs) only when documentation doesn't support a more specific option: larynx (D38.0), trachea, bronchus and lung (D38.1), pleura (D38.2), mediastinum (D38.3), thymus (D38.4) and respiratory organ, unspecified (D38.6).
Don't report D38.5 together with the conditions in its Excludes1 note: neoplasm of uncertain behavior of ear (external) (skin) (D48.5), neoplasm of uncertain behavior of nose NOS (D48.7) and neoplasm of uncertain behavior of skin of nose (D48.5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 180 (Respiratory Neoplasms with MCC, relative weight 1.7806), DRG 181 (Respiratory Neoplasms with CC, relative weight 1.0936) and DRG 182 (Respiratory Neoplasms without CC/MCC, relative weight 0.7439), in MDC 04 (Diseases and Disorders of the Respiratory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 235.9 (neoplasm of uncertain behavior of other and unspecified respiratory organs).
Coding notes
- Neoplasm of uncertain behavior of accessory sinuses
- Neoplasm of uncertain behavior of cartilage of nose
- Neoplasm of uncertain behavior of middle ear
- Neoplasm of uncertain behavior of nasal cavities
Notes that apply from higher levels
Instructions written at a parent level also apply to D38.5.
› From D38 Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs
- neoplasm of uncertain behavior of heart (D48.7)
Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.
Table of Drugs & Neoplasms entries
- Neoplasm, neoplastic › antrum (Highmore) (maxillary) — Uncertain Behavior
- Neoplasm, neoplastic › antrum (Highmore) (maxillary) › tympanicum — Uncertain Behavior
- Neoplasm, neoplastic › auditory › canal (external) (skin) › internal — Uncertain Behavior
- Neoplasm, neoplastic › auditory › tube — Uncertain Behavior
- Neoplasm, neoplastic › auricular canal (external) › internal — Uncertain Behavior
- Neoplasm, neoplastic › cartilage (articular) (joint) NEC › nose, nasal — Uncertain Behavior
- Neoplasm, neoplastic › cavity › nasal — Uncertain Behavior
- Neoplasm, neoplastic › cavity › tympanic — Uncertain Behavior
- Neoplasm, neoplastic › concha › nose — Uncertain Behavior
- Neoplasm, neoplastic › ear (external) › inner — Uncertain Behavior
- Neoplasm, neoplastic › ear (external) › middle — Uncertain Behavior
- Neoplasm, neoplastic › ethmoid (sinus) — Uncertain Behavior
- Neoplasm, neoplastic › eustachian tube — Uncertain Behavior
- Neoplasm, neoplastic › frontal › sinus — Uncertain Behavior
- Neoplasm, neoplastic › mastoid (air cells) (antrum) (cavity) — Uncertain Behavior
- Neoplasm, neoplastic › maxilla, maxillary (superior) › antrum — Uncertain Behavior
- Neoplasm, neoplastic › maxilla, maxillary (superior) › sinus — Uncertain Behavior
- Neoplasm, neoplastic › mucosa › nasal — Uncertain Behavior
- Neoplasm, neoplastic › nares, naris (anterior) (posterior) — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › cartilage — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › cavity — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › fossa — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › internal — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › mucosa — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › septum — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › turbinate (mucosa) — Uncertain Behavior
- Neoplasm, neoplastic › nose, nasal › vestibule — Uncertain Behavior
- Neoplasm, neoplastic › nostril — Uncertain Behavior
- Neoplasm, neoplastic › respiratory › tract NEC — Uncertain Behavior
- Neoplasm, neoplastic › respiratory › tract NEC › upper — Uncertain Behavior
Codes whose notes reference D38.5
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 04 · Diseases and Disorders of the Respiratory System
ICD-9-CM equivalent
Converter →- 235.9Neoplasm of uncertain behavior of other and unspecified respiratory organsapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about D38.5
Is D38.5 billable?
- Yes. D38.5 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D38.5 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D38.5 as a principal diagnosis.
Is D38.5 a CC or MCC?
- No. D38.5 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does D38.5 group to?
- D38.5 is used in the MS-DRG v44.0 logic for MS-DRG 180 (Respiratory Neoplasms with MCC), MS-DRG 181 (Respiratory Neoplasms with CC) and MS-DRG 182 (Respiratory Neoplasms without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for D38.5?
- The CMS General Equivalence Mappings map D38.5 to ICD-9-CM 235.9.