D48.1Neoplasm of uncertain behavior of connective and other soft tissue

D48.1 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of connective and other soft tissue. It belongs to category D48 (neoplasm of uncertain behavior of other and unspecified sites), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within D48, choose D48.1 (behavior of connective and other soft tissue) only when documentation doesn't support a more specific option: behavior of bone and articular cartilage (D48.0), behavior of peripheral nerves and autonomic nervous system (D48.2), behavior of retroperitoneum (D48.3), behavior of peritoneum (D48.4), behavior of skin (D48.5), behavior of breast (D48.6), behavior of other specified sites (D48.7) and behavior, unspecified (D48.9).

To report this condition, pick the subcode that matches the documentation: D48.11 (tumor) and D48.19 (tissue).

Don't report D48.1 together with the conditions in its Excludes1 note: neoplasm of uncertain behavior of articular cartilage (D48.0), neoplasm of uncertain behavior of cartilage of larynx (D38.0), neoplasm of uncertain behavior of cartilage of nose (D38.5) and neoplasm of uncertain behavior of connective tissue of breast (D48.6-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2024 (expanded into subcodes).

Before ICD-10, this condition was coded in ICD-9-CM as 238.1 (neoplasm of uncertain behavior of connective and other soft tissue).