ICD-10-CM 2027 diagnosis code

D48Neoplasm of uncertain behavior of other and unspecified sites

Not billable — use a more specific code

D48 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.Short description: Neoplasm of uncertain behavior of other and unsp sites

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D48

D48 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of other and unspecified sites. It belongs to block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D48.0 (cartilage), D48.1 (tissue), D48.2 (system), D48.3 (retroperitoneum), D48.4 (peritoneum), D48.5 (skin), D48.6 (breast), D48.7 (sites) and 1 more.

Don't report D48 together with the conditions in its Excludes1 note: neurofibromatosis (nonmalignant) (Q85.0-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D48

Coding notes

Excludes1Not coded here — never report together with this code

neurofibromatosis (nonmalignant) (Q85.0-)

Notes that apply from higher levels

Instructions written at a parent level also apply to D48.

Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.

Codes whose notes reference D48

D49Excludes2

Code history

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2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about D48

Is D48 billable?: No. D48 is a header code. Report one of its more specific subcodes instead.