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ICD-10-CM 2027 diagnosis code

D49.59Neoplasm of unspecified behavior of other genitourinary organ

✓ Billable / specific

D49.59 is a valid, billable ICD-10-CM code for neoplasm of unspecified behavior of other genitourinary organ. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Neoplasm of unspecified behavior of other GU organ

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D49.59

D49.59 is the ICD-10-CM diagnosis code for neoplasm of unspecified behavior of other genitourinary organ. It belongs to category D49 (neoplasms of unspecified behavior), block D49 (neoplasms of unspecified behavior) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D49.5, choose D49.59 (other genitourinary organ) only when documentation doesn't support a more specific option: kidney (D49.51).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 656 (Kidney and Ureter Procedures for Neoplasm with MCC, relative weight 3.2786), DRG 657 (Kidney and Ureter Procedures for Neoplasm with CC, relative weight 1.8365), DRG 658 (Kidney and Ureter Procedures for Neoplasm without CC/MCC, relative weight 1.538), DRG 686 (Kidney and Urinary Tract Neoplasms with MCC, relative weight 1.7237), DRG 687 (Kidney and Urinary Tract Neoplasms with CC, relative weight 0.9957) and DRG 688 (Kidney and Urinary Tract Neoplasms without CC/MCC, relative weight 0.7333), in MDC 11 (Diseases and Disorders of the Kidney and Urinary Tract), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2017, effective October 1, 2016.

Before ICD-10, this condition was coded in ICD-9-CM as 239.5 (neoplasm of unspecified nature of other genitourinary organs).

Notes that apply from higher levels

Instructions written at a parent level also apply to D49.59.

› From D49 Neoplasms of unspecified behavior
Note
  • Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.
Includes
  • 'growth' NOS
  • neoplasm NOS
  • new growth NOS
  • tumor NOS
Excludes2
  • neoplasms of uncertain behavior (D37-D44, D48)

Broader instructions also apply from Chapter 2: Neoplasms.

Table of Drugs & Neoplasms entries

Codes whose notes reference D49.59

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 239.5Neoplasm of unspecified nature of other genitourinary organsapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about D49.59

Is D49.59 billable?

Yes. D49.59 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D49.59 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D49.59 as a principal diagnosis.

Is D49.59 a CC or MCC?

No. D49.59 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does D49.59 group to?

D49.59 is used in the MS-DRG v44.0 logic for MS-DRG 656 (Kidney and Ureter Procedures for Neoplasm with MCC), MS-DRG 657 (Kidney and Ureter Procedures for Neoplasm with CC), MS-DRG 658 (Kidney and Ureter Procedures for Neoplasm without CC/MCC), MS-DRG 686 (Kidney and Urinary Tract Neoplasms with MCC), MS-DRG 687 (Kidney and Urinary Tract Neoplasms with CC) and MS-DRG 688 (Kidney and Urinary Tract Neoplasms without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for D49.59?

The CMS General Equivalence Mappings map D49.59 to ICD-9-CM 239.5.