ICD-10-CM 2027 diagnosis code

D49Neoplasms of unspecified behavior

Not billable — use a more specific code

D49 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About D49

D49 is the ICD-10-CM diagnosis code for neoplasms of unspecified behavior. It belongs to block D49 (neoplasms of unspecified behavior) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D49.0 (system), D49.1 (system), D49.2 (skin), D49.3 (breast), D49.4 (bladder), D49.5 (organs), D49.6 (brain), D49.7 (system) and 2 more.

The conditions in its Excludes2 note aren't part of D49, but may be coded alongside it if the patient has both: neoplasms of uncertain behavior (D37-D44, D48).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D49

Coding notes

Note

Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.

IncludesFurther defines the content of the category

'growth' NOS
neoplasm NOS
new growth NOS
tumor NOS

Excludes2Not included here — may be reported together if both conditions exist

neoplasms of uncertain behavior (D37-D44, D48)

Notes that apply from higher levels

Instructions written at a parent level also apply to D49.

Broader instructions also apply from Chapter 2: Neoplasms.

Codes whose notes reference D49

D63.0Code first
G13.0Code first
G13.1Code first
G32.8Code first
G32.81Code first
G53Code first
G55Code first
G63Code first
G73.1Code first
G73.3Code first
G91.4Code first
G99.2Code first
I31.31Code first
J91.0Code first
M36.0Code first

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about D49

Is D49 billable?: No. D49 is a header code. Report one of its more specific subcodes instead.