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ICD-10-CM 2027 diagnosis code

D59.32Hereditary hemolytic-uremic syndrome

D59.32 is a valid, billable ICD-10-CM code for hereditary hemolytic-uremic syndrome. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D59.32

D59.32 is the ICD-10-CM diagnosis code for hereditary hemolytic-uremic syndrome. It belongs to category D59 (acquired hemolytic anemia), block D55-D59 (hemolytic anemias) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D59.3 (hemolytic-uremic syndrome), D59.32 is specifically for hereditary hemolytic-uremic syndrome. Related codes cover unspecified (D59.30), infection-associated hemolytic-uremic syndrome (D59.31) and other hemolytic-uremic syndrome (D59.39).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period) and MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2023, effective October 1, 2022.

Coding notes

Applicable toConditions and synonyms classified to this code
  • Atypical hemolytic uremic syndrome with an identified genetic cause
Code alsoTwo codes may be needed; sequencing depends on circumstances
  • , if applicable:
  • defects in the complement system (D84.1)
  • methylmalonic acidemia (E71.120)

Notes that apply from higher levels

Instructions written at a parent level also apply to D59.32.

› From D59.3 Hemolytic-uremic syndrome
Code also
  • , if applicable, any associated:
  • acute kidney failure (N17.-)
  • chronic kidney disease (N18.-)

Broader instructions also apply from Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

Alphabetic index entries

5 entries

Terms in the official ICD-10-CM index that lead to D59.32.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period

MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period

MDC 16 · Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about D59.32

Is D59.32 billable?

Yes. D59.32 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D59.32 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D59.32 as a principal diagnosis.

Is D59.32 a CC or MCC?

D59.32 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does D59.32 group to?

D59.32 is used in the MS-DRG v44.0 logic for MS-DRG 791 (Prematurity with Major Problems), MS-DRG 793 (Full Term Neonate with Major Problems), MS-DRG 811 (Red Blood Cell Disorders with MCC) and MS-DRG 812 (Red Blood Cell Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.