ICD-10-CM 2027 · D55-D59

Hemolytic anemias

Part of chapter 3, diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

About D55-D59

Block D55-D59 contains 5 categories and 79 billable codes for FY2027. No codes here changed in the FY2027 update. 40 codes are MCCs and 11 are CCs when reported as secondary diagnoses.

D55Anemia due to enzyme disorders

D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
D55.1Anemia due to other disorders of glutathione metabolism
D55.2Anemia due to disorders of glycolytic enzymes
D55.3Anemia due to disorders of nucleotide metabolism
D55.8Other anemias due to enzyme disorders
D55.9Anemia due to enzyme disorder, unspecified

D56Thalassemia

D56.0Alpha thalassemia
D56.1Beta thalassemia
D56.2Delta-beta thalassemia
D56.3Thalassemia minor
D56.4Hereditary persistence of fetal hemoglobin [HPFH]
D56.5Hemoglobin E-beta thalassemia
D56.8Other thalassemias
D56.9Thalassemia, unspecified

D57Sickle-cell disorders

D57.0Hb-SS disease with crisis
D57.1Sickle-cell disease without crisis
D57.2Sickle-cell/Hb-C disease
D57.3Sickle-cell trait
D57.4Sickle-cell thalassemia
D57.8Other sickle-cell disorders

D58Other hereditary hemolytic anemias

D58.0Hereditary spherocytosis
D58.1Hereditary elliptocytosis
D58.2Other hemoglobinopathies
D58.8Other specified hereditary hemolytic anemias
D58.9Hereditary hemolytic anemia, unspecified

D59Acquired hemolytic anemia

D59.0Drug-induced autoimmune hemolytic anemia
D59.1Other autoimmune hemolytic anemias
D59.2Drug-induced nonautoimmune hemolytic anemia
D59.3Hemolytic-uremic syndrome
D59.4Other nonautoimmune hemolytic anemias
D59.5Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
D59.6Hemoglobinuria due to hemolysis from other external causes
D59.8Other acquired hemolytic anemias
D59.9Acquired hemolytic anemia, unspecified