D59.3Hemolytic-uremic syndrome

D59.3 is the ICD-10-CM diagnosis code for hemolytic-uremic syndrome. It belongs to category D59 (acquired hemolytic anemia), block D55-D59 (hemolytic anemias) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within D59 (acquired hemolytic anemia), D59.3 is specifically for hemolytic-uremic syndrome. Related codes cover drug-induced autoimmune hemolytic anemia (D59.0), other autoimmune hemolytic anemias (D59.1), drug-induced nonautoimmune hemolytic anemia (D59.2), other nonautoimmune hemolytic anemias (D59.4), paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] (D59.5), hemoglobinuria due to hemolysis from other external causes (D59.6), other acquired hemolytic anemias (D59.8) and unspecified (D59.9).

To report this condition, pick the subcode that matches the documentation: D59.30 (unspecified), D59.31 (syndrome), D59.32 (syndrome) and D59.39 (syndrome).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2023 (expanded into subcodes).

Before ICD-10, this condition was coded in ICD-9-CM as 283.11 (hemolytic-uremic syndrome).