D72.0Genetic anomalies of leukocytes

D72.0 is the ICD-10-CM diagnosis code for genetic anomalies of leukocytes. It belongs to category D72 (other disorders of white blood cells), block D70-D77 (other disorders of blood and blood-forming organs) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D72 (other disorders of white blood cells), D72.0 is specifically for genetic anomalies of leukocytes. Related codes cover eosinophilia (D72.1), other specified disorders of white blood cells (D72.8) and disorder of white blood cells, unspecified (D72.9).

Don't report D72.0 together with the conditions in its Excludes1 note: Chédiak (-Steinbrinck)-Higashi syndrome (E70.330).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 288.2 (genetic anomalies of leukocytes).