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ICD-10-CM 2027 diagnosis code

D80Immunodeficiency with predominantly antibody defects

Not billable — use a more specific code

D80 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D80

D80 is the ICD-10-CM diagnosis code for immunodeficiency with predominantly antibody defects. It belongs to block D80-D89 (certain disorders involving the immune mechanism) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D80.0 (hypogammaglobulinemia), D80.1 (hypogammaglobulinemia), D80.2 ([IgA]), D80.3 (subclasses), D80.4 ([IgM]), D80.5 ([IgM]), D80.6 (hyperimmunoglobulinemia), D80.7 (infancy) and 2 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D80

Notes that apply from higher levels

Instructions written at a parent level also apply to D80.

Broader instructions also apply from D80-D89 Certain disorders involving the immune mechanism and Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

Codes whose notes reference D80

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D80

Is D80 billable?

No. D80 is a header code. Report one of its more specific subcodes instead.