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ICD-10-CM 2027 diagnosis code

D89Other disorders involving the immune mechanism, not elsewhere classified

Not billable — use a more specific code

D89 is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.Short description: Oth disorders involving the immune mechanism, NEC

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D89

D89 is the ICD-10-CM diagnosis code for other disorders involving the immune mechanism, not elsewhere classified. It belongs to block D80-D89 (certain disorders involving the immune mechanism) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D89.0 (hypergammaglobulinemia), D89.1 (Cryoglobulinemia), D89.2 (unspecified), D89.3 (syndrome), D89.4 (disorders), D89.8 (classified) and D89.9 (unspecified).

Don't report D89 together with the conditions in its Excludes1 note: hyperglobulinemia NOS (R77.1) and monoclonal gammopathy (of undetermined significance) (D47.2).

The conditions in its Excludes2 note aren't part of D89, but may be coded alongside it if the patient has both: transplant failure and rejection (T86.-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D89

Coding notes

Excludes1Not coded here — never report together with this code
  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)
Excludes2Not included here — may be reported together if both conditions exist
  • transplant failure and rejection (T86.-)

Notes that apply from higher levels

Instructions written at a parent level also apply to D89.

Codes whose notes reference D89

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D89

Is D89 billable?

No. D89 is a header code. Report one of its more specific subcodes instead.