D75.821Non-immune heparin-induced thrombocytopenia

D75.821 is the ICD-10-CM diagnosis code for Non-immune heparin-induced thrombocytopenia. It belongs to category D75 (other and unspecified diseases of blood and blood-forming organs), block D70-D77 (other disorders of blood and blood-forming organs) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D75.82 (Heparin induced thrombocytopenia (HIT)), D75.821 is specifically for Non-immune heparin-induced thrombocytopenia. Related codes cover Immune-mediated heparin-induced thrombocytopenia (D75.822), other heparin-induced thrombocytopenia syndrome (D75.828) and heparin-induced thrombocytopenia, unspecified (D75.829).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195) and DRG 813 (Coagulation Disorders, relative weight 1.5257), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period) and MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2023, effective October 1, 2022.