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ICD-10-CM 2027 diagnosis code

I88.0Nonspecific mesenteric lymphadenitis

✓ Billable / specific

I88.0 is a valid, billable ICD-10-CM code for nonspecific mesenteric lymphadenitis. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Brennemann's syndrome, ICD-10 code for Mesenteric lymphadenitis.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I88.0

I88.0 is the ICD-10-CM diagnosis code for nonspecific mesenteric lymphadenitis. It belongs to category I88 (nonspecific lymphadenitis), block I80-I89 (diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified) and chapter 9 (diseases of the circulatory system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within I88 (nonspecific lymphadenitis), I88.0 is specifically for nonspecific mesenteric lymphadenitis. Related codes cover chronic lymphadenitis, except mesenteric (I88.1), other nonspecific lymphadenitis (I88.8) and unspecified (I88.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 393 (Other Digestive System Diagnoses with MCC, relative weight 1.5881), DRG 394 (Other Digestive System Diagnoses with CC, relative weight 0.9228) and DRG 395 (Other Digestive System Diagnoses without CC/MCC, relative weight 0.6382), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 289.2 (nonspecific mesenteric lymphadenitis).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Mesenteric lymphadenitis (acute)(chronic)

Notes that apply from higher levels

Instructions written at a parent level also apply to I88.0.

› From I88 Nonspecific lymphadenitis
Excludes1
  • acute lymphadenitis, except mesenteric (L04.-)
  • enlarged lymph nodes NOS (R59.-)
  • human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)

Broader instructions also apply from Chapter 9: Diseases of the circulatory system.

Alphabetic index entries

7 entries

Terms in the official ICD-10-CM index that lead to I88.0.

Codes whose notes reference I88.0

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 289.2Nonspecific mesenteric lymphadenitisexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about I88.0

Is I88.0 billable?

Yes. I88.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can I88.0 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict I88.0 as a principal diagnosis.

Is I88.0 a CC or MCC?

No. I88.0 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does I88.0 group to?

I88.0 is used in the MS-DRG v44.0 logic for MS-DRG 393 (Other Digestive System Diagnoses with MCC), MS-DRG 394 (Other Digestive System Diagnoses with CC) and MS-DRG 395 (Other Digestive System Diagnoses without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for I88.0?

The CMS General Equivalence Mappings map I88.0 to ICD-9-CM 289.2.