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ICD-10-CM 2027 diagnosis code

E29.1Testicular hypofunction

✓ Billable / specificMale only

E29.1 is a valid, billable ICD-10-CM code for testicular hypofunction. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Eunuchoidism, ICD-10 code for Panhypogonadism.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E29.1

E29.1 is the ICD-10-CM diagnosis code for testicular hypofunction. It belongs to category E29 (testicular dysfunction), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E29 (testicular dysfunction), E29.1 is specifically for testicular hypofunction. Related codes cover testicular hyperfunction (E29.0), other testicular dysfunction (E29.8) and unspecified (E29.9).

Don't report E29.1 together with the conditions in its Excludes1 note: postprocedural testicular hypofunction (E89.5).

Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is on the CMS list of diagnoses consistent only with male patients (the sex-conflict edit itself was retired in FY2025).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 257.2 (other testicular hypofunction).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Defective biosynthesis of testicular androgen NOS
  • 5-Alpha-reductase deficiency (with male pseudohermaphroditism)
  • Testicular hypogonadism NOS
Excludes1Not coded here — never report together with this code
  • postprocedural testicular hypofunction (E89.5)
Use additional codeAdd a secondary code to fully describe the condition
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes that apply from higher levels

Instructions written at a parent level also apply to E29.1.

› From E29 Testicular dysfunction
Excludes1

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

18 entries

Terms in the official ICD-10-CM index that lead to E29.1.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 257.2Other testicular hypofunctionexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E29.1

Is E29.1 billable?

Yes. E29.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E29.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E29.1 as a principal diagnosis.

Is E29.1 a CC or MCC?

No. E29.1 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E29.1 group to?

E29.1 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC) and MS-DRG 645 (Endocrine Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E29.1?

The CMS General Equivalence Mappings map E29.1 to ICD-9-CM 257.2.