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ICD-10-CM 2027 diagnosis code

E89.1Postprocedural hypoinsulinemia

✓ Billable / specificCC — complication/comorbidity

E89.1 is a valid, billable ICD-10-CM code for postprocedural hypoinsulinemia. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Hypoinsulinemia.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E89.1

E89.1 is the ICD-10-CM diagnosis code for postprocedural hypoinsulinemia. It belongs to category E89 (postprocedural endocrine and metabolic complications and disorders, not elsewhere classified), block E89 (postprocedural endocrine and metabolic complications and disorders, not elsewhere classified) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E89 (postprocedural endocrine and metabolic complications and disorders, not elsewhere classified), E89.1 is specifically for postprocedural hypoinsulinemia. Related codes cover postprocedural hypothyroidism (E89.0), postprocedural hypoparathyroidism (E89.2), postprocedural hypopituitarism (E89.3), postprocedural ovarian failure (E89.4), postprocedural testicular hypofunction (E89.5), postprocedural adrenocortical (-medullary) hypofunction (E89.6) and other postprocedural endocrine and metabolic complications and disorders (E89.8).

Don't report E89.1 together with the conditions in its Excludes1 note: transient postprocedural hyperglycemia (R73.9) and transient postprocedural hypoglycemia (E16.2).

Code first: , if applicable, diabetes mellitus (postpancreatectomy) (postprocedural) (E13.-).

Use an additional code, if applicable, to identify: acquired absence of pancreas (Z90.41-) and insulin use (Z79.4).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395) and DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), in Pre-MDC and MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 251.3 (postsurgical hypoinsulinemia).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Postpancreatectomy hyperglycemia
  • Postsurgical hypoinsulinemia
Excludes1Not coded here — never report together with this code
  • transient postprocedural hyperglycemia (R73.9)
  • transient postprocedural hypoglycemia (E16.2)
Code firstSequence the underlying condition first
  • , if applicable, diabetes mellitus (postpancreatectomy) (postprocedural) (E13.-)
Use additional codeAdd a secondary code to fully describe the condition
  • code, if applicable, to identify:
  • acquired absence of pancreas (Z90.41-)
  • insulin use (Z79.4)

Notes that apply from higher levels

Instructions written at a parent level also apply to E89.1.

› From E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified
Excludes2
  • intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)

Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

7 entries

Terms in the official ICD-10-CM index that lead to E89.1.

Codes whose notes reference E89.1

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 251.3Postsurgical hypoinsulinemiaexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E89.1

Is E89.1 billable?

Yes. E89.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E89.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E89.1 as a principal diagnosis.

Is E89.1 a CC or MCC?

E89.1 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E89.1 group to?

E89.1 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC) and MS-DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E89.1?

The CMS General Equivalence Mappings map E89.1 to ICD-9-CM 251.3.