ICD-10-CM 2027 diagnosis code

I88Nonspecific lymphadenitis

Not billable — use a more specific code

I88 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I88

I88 is the ICD-10-CM diagnosis code for nonspecific lymphadenitis. It belongs to block I80-I89 (diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified) and chapter 9 (diseases of the circulatory system). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: I88.0 (lymphadenitis), I88.1 (mesenteric), I88.8 (lymphadenitis) and I88.9 (unspecified).

Don't report I88 together with the conditions in its Excludes1 note: acute lymphadenitis, except mesenteric (L04.-), enlarged lymph nodes NOS (R59.-) and human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under I88

Coding notes

Excludes1Not coded here — never report together with this code

acute lymphadenitis, except mesenteric (L04.-)
enlarged lymph nodes NOS (R59.-)
human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)

Notes that apply from higher levels

Instructions written at a parent level also apply to I88.

Broader instructions also apply from Chapter 9: Diseases of the circulatory system.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about I88

Is I88 billable?: No. I88 is a header code. Report one of its more specific subcodes instead.