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ICD-10-CM 2027 diagnosis code

M35.00Sjogren syndrome, unspecified

✓ Billable / specific

M35.00 is a valid, billable ICD-10-CM code for sjogren syndrome, unspecified. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2022 (effective October 1, 2021). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About M35.00

M35.00 is the ICD-10-CM diagnosis code for Sjogren syndrome, unspecified. It belongs to category M35 (other systemic involvement of connective tissue), block M30-M36 (systemic connective tissue disorders) and chapter 13 (diseases of the musculoskeletal system and connective tissue). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within M35.0, choose M35.00 (unspecified) only when documentation doesn't support a more specific option: with keratoconjunctivitis (M35.01), with lung involvement (M35.02), with myopathy (M35.03), with tubulo-interstitial nephropathy (M35.04), with inflammatory arthritis (M35.05), with peripheral nervous system involvement (M35.06), with central nervous system involvement (M35.07), with gastrointestinal involvement (M35.08) and 4 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 545 (Connective Tissue Disorders with MCC, relative weight 2.3892), DRG 546 (Connective Tissue Disorders with CC, relative weight 1.1745) and DRG 547 (Connective Tissue Disorders without CC/MCC, relative weight 0.7526), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2022 (title revised).

Before ICD-10, this condition was coded in ICD-9-CM as 710.2 (sicca syndrome).

Notes that apply from higher levels

Instructions written at a parent level also apply to M35.00.

› From M35.0 Sjogren syndrome
Excludes1
  • dry mouth, unspecified (R68.2)
Use additional code
  • code to identify associated manifestations
› From M35 Other systemic involvement of connective tissue
Excludes1
  • reactive perforating collagenosis (L87.1)

Broader instructions also apply from M30-M36 Systemic connective tissue disorders and Chapter 13: Diseases of the musculoskeletal system and connective tissue.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to M35.00.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 710.2Sicca syndromeapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2022 (effective 10/1/2021): Title revised — was “Sicca syndrome, unspecified”

Common questions about M35.00

Is M35.00 billable?

Yes. M35.00 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can M35.00 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict M35.00 as a principal diagnosis.

Is M35.00 a CC or MCC?

No. M35.00 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does M35.00 group to?

M35.00 is used in the MS-DRG v44.0 logic for MS-DRG 545 (Connective Tissue Disorders with MCC), MS-DRG 546 (Connective Tissue Disorders with CC) and MS-DRG 547 (Connective Tissue Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for M35.00?

The CMS General Equivalence Mappings map M35.00 to ICD-9-CM 710.2.