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ICD-10-CM 2027 diagnosis code

M35Other systemic involvement of connective tissue

Not billable — use a more specific code

M35 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About M35

M35 is the ICD-10-CM diagnosis code for other systemic involvement of connective tissue. It belongs to block M30-M36 (systemic connective tissue disorders) and chapter 13 (diseases of the musculoskeletal system and connective tissue). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: M35.0 (syndrome), M35.1 (syndromes), M35.2 (disease), M35.3 (rheumatica), M35.4 (fasciitis), M35.5 (fibrosclerosis), M35.6 ([Weber-Christian]), M35.7 (syndrome) and 2 more.

Don't report M35 together with the conditions in its Excludes1 note: reactive perforating collagenosis (L87.1).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under M35

Coding notes

Excludes1Not coded here — never report together with this code
  • reactive perforating collagenosis (L87.1)

Notes that apply from higher levels

Instructions written at a parent level also apply to M35.

Broader instructions also apply from M30-M36 Systemic connective tissue disorders and Chapter 13: Diseases of the musculoskeletal system and connective tissue.

Codes whose notes reference M35

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about M35

Is M35 billable?

No. M35 is a header code. Report one of its more specific subcodes instead.