T45.8Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents

T45.8 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents. It belongs to category T45 (poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 1 subcodes must be used instead.

Within T45, choose T45.8 (other primarily systemic and hematological agents) only when documentation doesn't support a more specific option: antiallergic and antiemetic drugs (T45.0), antineoplastic and immunosuppressive drugs (T45.1), vitamins (T45.2), enzymes (T45.3), iron and its compounds (T45.4), anticoagulants and antithrombotic drugs (T45.5), fibrinolysis-affecting drugs (T45.6), anticoagulant antagonists, vitamin K and other coagulants (T45.7) and 2 more.

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

The conditions in its Excludes2 note aren't part of T45.8, but may be coded alongside it if the patient has both: poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1), poisoning by, adverse effect of and underdosing of iron (T45.4) and transfusion reactions (T80.-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.