ICD-10-CM 2027 diagnosis code
T45.8X6Underdosing of other primarily systemic and hematological agents
T45.8X6 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Underdosing of primarily systemic and hematological agents
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T45.8X6
T45.8X6 is the ICD-10-CM diagnosis code for underdosing of other primarily systemic and hematological agents. It belongs to category T45 (poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T45.8X, choose T45.8X6 (Underdosing of other primarily systemic and hematological agents) only when documentation doesn't support a more specific option: poisoning by other primarily systemic and hematological agents, accidental (unintentional) (T45.8X1), poisoning by other primarily systemic and hematological agents, intentional self-harm (T45.8X2), poisoning by other primarily systemic and hematological agents, assault (T45.8X3), poisoning by other primarily systemic and hematological agents, undetermined (T45.8X4) and adverse effect of other primarily systemic and hematological agents (T45.8X5).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T45
Notes that apply from higher levels
Instructions written at a parent level also apply to T45.8X6.
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Table of Drugs & Neoplasms entries
- Albumin › bovine — Underdosing
- Albumin › human serum — Underdosing
- Albumin › human serum › salt-poor — Underdosing
- Albumin › normal human serum — Underdosing
- Aminoethylisothiourium — Underdosing
- Antagonist › heavy metal — Underdosing
- Anti-anemic (drug) (preparation) — Underdosing
- Antidote NEC › heavy metal — Underdosing
- Antihemophilic › factor — Underdosing
- Antihemophilic › fraction — Underdosing
- Antihemophilic › human plasma — Underdosing
- BAL — Underdosing
- Blood (derivatives) (natural) (plasma) (whole) — Underdosing
- Blood (derivatives) (natural) (plasma) (whole) › dried — Underdosing
- Blood (derivatives) (natural) (plasma) (whole) › expander NEC — Underdosing
- Blood (derivatives) (natural) (plasma) (whole) › fraction NEC — Underdosing
- Blood (derivatives) (natural) (plasma) (whole) › substitute (macromolecular) — Underdosing
- British antilewisite — Underdosing
- Calcium › disodium edathamil — Underdosing
- Calcium › disodium edetate — Underdosing
- Calcium › EDTA — Underdosing
- Calcium › folinate — Underdosing
- Calcium › leucovorin — Underdosing
- Citrovorum (factor) — Underdosing
- Cobalt (nonmedicinal) (fumes) (industrial) › medicinal (trace) (chloride) — Underdosing
- Copper (dust) (fumes) (nonmedicinal) NEC › medicinal (trace) — Underdosing
- Cyanocobalamin — Underdosing
- Deferoxamine — Underdosing
- Desferrioxamine — Underdosing
- Dextran (40) (70) (150) — Underdosing
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T45.8X6
Is T45.8X6 billable?
- No. T45.8X6 is a header code. Report one of its more specific subcodes instead.