ICD-10-CM 2027 diagnosis code
T46.4Poisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitors
T46.4 is a header code, so it can't be reported by itself. Choose one of the 1 more specific codes beneath it and add the required 7th character.Short description: Angiotensin-converting-enzyme inhibitors
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T46.4
T46.4 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitors. It belongs to category T46 (poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 1 subcodes must be used instead.
Within T46 (poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system), T46.4 is specifically for poisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitors. Related codes cover cardiac-stimulant glycosides and drugs of similar action (T46.0), calcium-channel blockers (T46.1), other antidysrhythmic drugs, not elsewhere classified (T46.2), coronary vasodilators (T46.3), other antihypertensive drugs (T46.5), antihyperlipidemic and antiarteriosclerotic drugs (T46.6), peripheral vasodilators (T46.7), antivaricose drugs, including sclerosing agents (T46.8) and 1 more.
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T46
- T46.4XPoisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitors
- T46.4X1Poisoning by angiotensin-converting-enzyme inhibitors, accidental (unintentional)
- T46.4X2Poisoning by angiotensin-converting-enzyme inhibitors, intentional self-harm
- T46.4X3Poisoning by angiotensin-converting-enzyme inhibitors, assault
- T46.4X4Poisoning by angiotensin-converting-enzyme inhibitors, undetermined
- T46.4X5Adverse effect of angiotensin-converting-enzyme inhibitors
- T46.4X6Underdosing of angiotensin-converting-enzyme inhibitors
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Notes that apply from higher levels
Instructions written at a parent level also apply to T46.4.
› From T46 Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system
- poisoning by, adverse effect of and underdosing of metaraminol (T44.4)
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T46.4
Is T46.4 billable?
- No. T46.4 is a header code. Report one of its more specific subcodes instead.