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ICD-10-CM 2027 diagnosis code

Z91.BPersonal risk factor of exposure to diethylstilbestrol

✓ Billable / specificPOA exemptNot a principal dx

Z91.B is a valid, billable ICD-10-CM code for personal risk factor of exposure to diethylstilbestrol. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Z91.B

Z91.B is the ICD-10-CM diagnosis code for personal risk factor of exposure to diethylstilbestrol. It belongs to category Z91 (personal risk factors, not elsewhere classified), block Z77-Z99 (persons with potential health hazards related to family and personal history and certain conditions influencing health status) and chapter 21 (factors influencing health status and contact with health services). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within Z91 (personal risk factors, not elsewhere classified), Z91.B is specifically for personal risk factor of exposure to diethylstilbestrol. Related codes cover allergy status, other than to drugs and biological substances (Z91.0), patient's noncompliance with medical treatment and regimen (Z91.1), personal history of psychological trauma, not elsewhere classified (Z91.4), personal history of self-harm (Z91.5), other specified personal risk factors, not elsewhere classified (Z91.8) and Caregiver's noncompliance with patient's medical treatment and regimen (Z91.A).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.

It was added in FY2026, effective October 1, 2025.

Coding notes

Applicable toConditions and synonyms classified to this code
  • DES daughter or son
  • Personal risk factor of exposure to DES
  • Personal risk factor of exposure to DES in utero
  • Second generation DES exposure
Code alsoTwo codes may be needed; sequencing depends on circumstances
  • , associated conditions, such as:
  • conditions classifiable to C50.-
  • osteoporosis (M80.-)
  • premature menopause (E28.31-)

Notes that apply from higher levels

Instructions written at a parent level also apply to Z91.B.

› From Z91 Personal risk factors, not elsewhere classified
Excludes2
  • contact with and (suspected) exposures hazardous to health (Z77.-)
  • exposure to pollution and other problems related to physical environment (Z77.1-)
  • female genital mutilation status (N90.81-)
  • occupational exposure to risk factors (Z57.-)
  • personal history of physical injury and trauma (Z87.81, Z87.82-)

Broader instructions also apply from Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status and Chapter 21: Factors influencing health status and contact with health services.

Alphabetic index entries

3 entries

Terms in the official ICD-10-CM index that lead to Z91.B.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about Z91.B

Is Z91.B billable?

Yes. Z91.B is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can Z91.B be used as a principal diagnosis?

No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

Is Z91.B a CC or MCC?

No. Z91.B is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does Z91.B group to?

Z91.B is used in the MS-DRG v44.0 logic for MS-DRG 951 (Other Factors Influencing Health Status). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.