ICD-10-CM 2027
ICD-10 code for adrenal dysfunction
From the official ICD-10-CM alphabetic index entry “Dysfunction › adrenal”. Page updated September 29, 2026.
About coding adrenal dysfunction
The ICD-10-CM code for adrenal dysfunction is E27.9 (Disorder of adrenal gland, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on E27.9.
Within E27, choose E27.9 (Disorder of adrenal gland, unspecified) only when documentation doesn't support a more specific option: other adrenocortical overactivity (E27.0), primary adrenocortical insufficiency (E27.1), Addisonian crisis (E27.2), drug-induced adrenocortical insufficiency (E27.3), other and unspecified adrenocortical insufficiency (E27.4), Adrenomedullary hyperfunction (E27.5) and other specified disorders of adrenal gland (E27.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific adrenal dysfunction codes (official index)
- hyperfunction E27.0 — Other adrenocortical overactivity
Common questions about adrenal dysfunction ICD-10 codes
What is the ICD-10 code for adrenal dysfunction?
- E27.9 — Disorder of adrenal gland, unspecified. More specific codes apply when the documentation supports them: E27.0.
What is the ICD-10 code for hyperfunction adrenal dysfunction?
- E27.0 — Other adrenocortical overactivity.
Is E27.9 billable?
- Yes. E27.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E27.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E27.9 as a principal diagnosis.
Is E27.9 a CC or MCC?
- No. E27.9 is neither a CC nor an MCC under MS-DRG v44.0.