E27.4Other and unspecified adrenocortical insufficiency

E27.4 is the ICD-10-CM diagnosis code for other and unspecified adrenocortical insufficiency. It belongs to category E27 (other disorders of adrenal gland), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within E27, choose E27.4 (Other and unspecified adrenocortical insufficiency) only when documentation doesn't support a more specific option: other adrenocortical overactivity (E27.0), primary adrenocortical insufficiency (E27.1), Addisonian crisis (E27.2), drug-induced adrenocortical insufficiency (E27.3), Adrenomedullary hyperfunction (E27.5), other specified disorders of adrenal gland (E27.8) and disorder of adrenal gland, unspecified (E27.9).

To report this condition, pick the subcode that matches the documentation: E27.40 (insufficiency) and E27.49 (insufficiency).

Don't report E27.4 together with the conditions in its Excludes1 note: adrenoleukodystrophy [Addison-Schilder] (E71.528) and Waterhouse-Friderichsen syndrome (A39.1).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.