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ICD-10-CM 2027 diagnosis code

E27.2Addisonian crisis

✓ Billable / specificCC — complication/comorbidity

E27.2 is a valid, billable ICD-10-CM code for addisonian crisis. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Addisonian crisis.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E27.2

E27.2 is the ICD-10-CM diagnosis code for Addisonian crisis. It belongs to category E27 (other disorders of adrenal gland), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E27 (other disorders of adrenal gland), E27.2 is specifically for Addisonian crisis. Related codes cover other adrenocortical overactivity (E27.0), primary adrenocortical insufficiency (E27.1), drug-induced adrenocortical insufficiency (E27.3), other and unspecified adrenocortical insufficiency (E27.4), Adrenomedullary hyperfunction (E27.5), other specified disorders of adrenal gland (E27.8) and disorder of adrenal gland, unspecified (E27.9).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 255.41 (Glucocorticoid deficiency).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Adrenal crisis
  • Adrenocortical crisis

Notes that apply from higher levels

Instructions written at a parent level also apply to E27.2.

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

5 entries

Terms in the official ICD-10-CM index that lead to E27.2.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 255.41Glucocorticoid deficiencyapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E27.2

Is E27.2 billable?

Yes. E27.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E27.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E27.2 as a principal diagnosis.

Is E27.2 a CC or MCC?

E27.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E27.2 group to?

E27.2 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC) and MS-DRG 645 (Endocrine Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E27.2?

The CMS General Equivalence Mappings map E27.2 to ICD-9-CM 255.41.