ICD-10 code for antibody deficiency syndrome

The ICD-10-CM code for antibody deficiency syndrome is D80.9 (Immunodeficiency with predominantly antibody defects, unspecified). The official index lists 5 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D80.9.

Within D80, choose D80.9 (unspecified) only when documentation doesn't support a more specific option: hereditary hypogammaglobulinemia (D80.0), nonfamilial hypogammaglobulinemia (D80.1), selective deficiency of immunoglobulin A [IgA] (D80.2), selective deficiency of immunoglobulin G [IgG] subclasses (D80.3), selective deficiency of immunoglobulin M [IgM] (D80.4), immunodeficiency with increased immunoglobulin M [IgM] (D80.5), antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia (D80.6), transient hypogammaglobulinemia of infancy (D80.7) and 1 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.