ICD-10-CM 2027
ICD-10 code for Bilirubinemia
From the official ICD-10-CM alphabetic index entry “Bilirubinemia, familial nonhemolytic”. Page updated September 29, 2026.
About coding Bilirubinemia
The ICD-10-CM code for Bilirubinemia is E80.4 (Gilbert syndrome).
Within E80 (disorders of porphyrin and bilirubin metabolism), E80.4 is specifically for Gilbert syndrome. Related codes cover hereditary erythropoietic porphyria (E80.0), porphyria cutanea tarda (E80.1), other and unspecified porphyria (E80.2), defects of catalase and peroxidase (E80.3), Crigler-Najjar syndrome (E80.5), other disorders of bilirubin metabolism (E80.6) and disorder of bilirubin metabolism, unspecified (E80.7).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 441 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC, relative weight 1.8219), DRG 442 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with CC, relative weight 0.9602) and DRG 443 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis without CC/MCC, relative weight 0.6885), in MDC 07 (Diseases and Disorders of the Hepatobiliary System and Pancreas), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Bilirubinemia ICD-10 codes
What is the ICD-10 code for Bilirubinemia?
- E80.4 — Gilbert syndrome.
Is E80.4 billable?
- Yes. E80.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E80.4 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E80.4 as a principal diagnosis.
Is E80.4 a CC or MCC?
- No. E80.4 is neither a CC nor an MCC under MS-DRG v44.0.